… -5 versus ADAMTS-4 in human OA cartilage explants [12]. … was assessed in bovine cartilage
and OA human cartilage explants. … ADAMTS-5 in cartilage ex vivo models to characterize its …

… Bovine cartilage explants were cultured with oncostatin M (… effects on the cartilage ECM,
by measuring the translational … turnover is characterized by cartilage tissue deterioration. This …

… ) whose activities were phenotypically measured by ELISA (enzyme-… analysis of gene
expression for the main ECM component, aggrecan and their proteinase, aggrecanase (ADAMTS-4…

… Our in vitro model consists of cultured bovine cartilage explants … for measuring active
metalloproteases in the PTOA model. Our … Furthermore, our analysis of MMP activities in a model …

… Healthy bovine cartilage explants were cultured with the … 80 C prior to ELISA measurements
and ex vivo experiments. Steps … ) released by the aggrecanases ADAMTS-4 and -5 from the …

… In this study, we aimed to characterize an antibody targeting … to enhance cartilage synthesis
in the settings of in vitro [12], ex vivo [13… The PIIANP assay is a competitive ELISA based on a …

… Therefore, we used the mice to model FJ-OA and test the … analysis showed an increase in
total cartilage area after VAP … by down regulate MMP-13, ADAMTS-4 and ADAMTS-5 mRNA …

… In addition, function of α2 M on TNF-α-treated ex vivo IVDs … This study characterized the
changes in expression of α2 M and … Involvement of ADAMTS-5, but not ADAMTS-4, was in the …

… synthesized cartilage is higher than in the normal cartilage … developed specific assays for
the active forms of ADAMTS-4, … models in large and well-characterized prospective studies. …

… Scaffolds were characterized in vitro and then deployed in a … Future in vitro studies could
use ELISA assays to measure the … that the in vitro assays were performed with bovine MSC's, …